Certified Clinical Hemodialysis Technician (CCHT) Practice Exam 2025 – The All-in-One Guide to Exam Success!

In long-term dialysis patients, excessive levels of beta2-microglobulin are strongly associated with amyloidosis, specifically dialysis-related amyloidosis (DRA). This condition arises due to the accumulation of beta2-microglobulin in the body, as it is not adequately cleared by dialysis. Over time, the excess beta2-microglobulin can misfold and aggregate, leading to the formation of amyloid deposits in various tissues, particularly in the joints and tendons. This results in symptoms such as joint pain and stiffness, which are characteristic of amyloidosis.

Understanding the specific role of beta2-microglobulin in this context is essential for managing the health of long-term dialysis patients. Monitoring its levels can help healthcare providers identify and address the risk of amyloidosis early, thereby improving patient outcomes and quality of life.